| ORIGINAL ARTICLE |
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| Year : 2022 | Volume
: 9
| Issue : 4 | Page : 258-261 |
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Evaluation of the analgesic effect of oral sucrose solution on neonates undergoing a minor painful procedure
Kallol Paul1, Pankaj Kumar Halder2, Rituparna Das3, Arpita Choudhury4, Prerna Goenka5, Sourav Roy2
1 Department of Pediatric Medicine, College of Medicine and Sagore Dutta Hospital, Kolkata, West Bengal, India
2 Department of Pediatric Surgery, R G Kar Medical College, Kolkata, West Bengal, India
3 Department of Anesthesiology and Critical Care, ESIC Medical College and Hospital, Kolkata, West Bengal, India
4 Department of Anesthesiology, R G Kar Medical College, Kolkata, West Bengal, India
5 Department of Pediatric Medicine, SSKM and IPGMER, Kolkata, West Bengal, India
Correspondence Address:
Pankaj Kumar Halder
Saroda Pally, Baruipur, Kolkata - 700 144, West Bengal
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/cjhr.cjhr_14_22
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Background: Pacifying newborns by nonpharmacological methods during painful procedures is a frequent and difficult problem in routine practice. Purpose: The purpose of the study was to determine the analgesic effects of oral sucrose solution in comparison to placebo (sterile water) in neonates. Materials and Methods: A prospective, double-blinded study of 100 neonates who were divided into two groups after simple randomization, to give either 30% sucrose solution (group A) or sterile water (group B) during an intravenous catheterization. Assessment of pain by the Douleur Aigue Nouveau-ne scale (DAN) and changes in the heart rate (HR), respiratory rate (RR), or arterial oxygen saturation (SpO2) during peripheral vein catheterization were analyzed. Results: The mean change of HR, RR, and SpO2 was more in group B compared to group A. The mean DAN scores were 2.24 ± 2.026 and 6.92 ± 2.538 in group A and group B, respectively. None of these results were statistically significant (P > 0.05). Conclusion: There was a less prominent change in HR, RR, and SpO2 with response to noxious stimuli with oral sucrose administration in newborns when compared to placebo.
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